This patient developed bloody stool whilst on holiday in Africa. They continue on return home and he undergo a flexible sigmoidoscopy. Of course, stool samples are obtained (last image).
WHAT IS THE PATHOGEN?
a) Clostridium difficile
Can be seen moving down a microscope
b) Salmonella enterica
Can give bloody diarrhoea but its not it!
c) Entamoeba histiolytica
Rasberry stool, to be examined warm
d) Campylobacter jejuni
May also give bloody stool but that's not it
e) Vibrio cholerae
Hmm, rice-water stool...
explanation
Let me give you some more clues! Classically, there are 'flask-shaped' ulcers found on resectional histology in which the mucosal surface ulcer is rather narrow with a wider, necrotic submucosal component in which the amoeba multiply. Stools have been described as like "Raspberry jam" and when examined whilst still warm, something can be seen moving. Of course PCR is the best way of confirming the diagnosis.
This patient had amoebic dysentery! Mild cases can resolve without metronidazole. |
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