Flip, is achalasia a viral infection and a Sheffield turnaround

​We are reporting on the 'FLIP device' and give you an update on the likely aetiology of achalasia. There have been studies on 'motorised spiral enteroscopy'. Is a motor really a good thing inside the small bowel?  e are surprised to see a complete turnaround in the recommendations from Sheffield on how to diagnose Coeliac disease !  Sadly, surveillance in patients with MUTyH related polyposis doesn't seem to save lives. Should we all start doing 'full thickness' colonic resections?  I urge caution!  Finally, there have been some good news and some bad news on the topic of emergency GI bleeding ..

References

New insights

• Savarino E. T Use of the Functional Lumen Imaging Probe.  American Journal of Gastroenterology 2020;115(11):1786-1796
• Campagna RAJ. Intraoperative assessment of oesophageal motility using FLIP during myotomy for achalasia.  Surgical Endoscopy 2020;34(6):2593-2600
• Ikebuchi Y. microRNAs in biopsy samples of lower oesophageal sphincter muscle during peroral endoscopic myotomy for oesophageal achalasia.  Digestive Endoscopy. 2020;32(1):136-142
• New Equipment
• Ramchandani M. Diagnostic yield and therapeutic impact of novel motorized spiral enteroscopy in small-bowel disorders: a single-center, real-world experience from a tertiary care hospital (with video).  Gastrointestinal Endoscopy.  2020 Jul 12.
• Beyna T. Total motorized spiral enteroscopy: first prospective clinical feasibility trial.  Gastrointestinal Endoscopy.  2020 Oct 31.

New Thinking

• Penny HA. Accuracy of a no-biopsy approach for the diagnosis of coeliac disease across different adult cohorts. Gut 2020 Nov 02.
• Guz-Mark A. High rates of serology testing for coeliac disease, and low rates of endoscopy in serologically positive children and adults in Israel: lessons from a large real-world database.  European Journal of Gastroenterology & Hepatology. 2020;32(3):329-334
• Thomas LE.  Duodenal adenomas and cancer in MUTYH-associated polyposis: an international cohort study.  Gastroenterology.  2020 Oct 29.
• Patel R.  MUTYH-associated polyposis - colorectal phenotype and management.  Colorectal Disease 2020;22(10):1271-1278

Therapeutics

• Yeh JH.  Long-term Outcomes of Primary Endoscopic Resection vs Surgery for T1 Colorectal Cancer: A Systematic Review and Meta-analysis.  Clinical Gastroenterology & Hepatology. 2020;18(12):2813-2823
• Boger P.  Endoscopic full thickness resection in the colo-rectum: outcomes from the UK Registry. European Journal of Gastroenterology & Hepatology.  2020 Oct 29.
• Zwager LW.  Endoscopic full-thickness resection (eFTR) of colorectal lesions: results from the Dutch colorectal eFTR registry.  Endoscopy. 2020;52(11):1014-1023
• Lee HS.  Comparison of conventional and modified endoscopic mucosal resection methods for the treatment of rectal neuroendocrine tumors.  Surgical Endoscopy.  2020 Oct 22.
  
  

GI Bleeding

• Kherad O. Systematic review with meta-analysis: limited benefits from early colonoscopy in acute lower gastrointestinal bleeding. [Review] Alimentary Pharmacology & Therapeutics. 52(5):774-788, 2020 09.
• Alzoubadi D. Outcomes from an international multicenter registry of patients with acute gastrointestinal bleeding undergoing endoscopic treatment with Hemospray.  Digestive Endoscopy. 2020;32(1):96-105