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Friends of Endoscopy is all about pattern recognition.  See it today and recognise it tomorrow!   Learn from a New Case on most weekdays !!! 
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A rather uninteresting looking polyp?

14/7/2021

Comments

 
Picture
A polyp found in the descending colon and removed as a single fragment (H&E attached)
WHAT IS THE DIAGNOSIS
a) Tubular adenoma
Yes but you are only partly correct!
b) Tubulovillous adenoma
No way, this is a LST-NG!!!
c) Villous adenoma
Absolutely not - there are no villi!!!
d) Sessile serrated lesion
Looks like it but histology doesn't!
e) Malignant polyp
Full marks!
explanation
​This is a LST-NG type of lesion (laterally spreading tumour of the non-granular type). They are always TA's (tubular adenomas) and often (but usually not), harbour HGD or cancer. I guess that we can't really be sure about the crypt pattern as this is a non-magnified image. However, looking at the histology slide with narrow crypts, I expect that the crypt pattern is probably IIIs (small round crypts) which goes with TA+HGD. Must admit that I was surprised to find invasive cancer and LVI (lymphovascular invasion) in a small lesion such as this! The last image shows clusters of malignant cells within lymphatics. Of all the 'markers' to suggest that the patient needs surgery, LVI is the most important!
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    Categories

    All
    Barrett's
    Cancer
    Cancer Syndromes
    Colitis
    Colorectum
    Corrosive Ingestion
    Crypt Pattern
    Difficulty: Hard
    Difficulty: Moderate
    Difficulty: Very Hard
    Duodenum
    Eosinophilic Oesophagitis
    EUS
    Foveolar Metaplasia
    Gastric
    Gastroscopy
    GI Bleeding
    Histology
    HPB
    Ileum
    Immunosuppression
    Infection
    Local Recurrence Of Barrett's Ca.
    Lymphoma
    Mixed Polyp
    Mucosal Prolapse Syndrome
    NET
    Non-lifting Sign
    Oesophagus
    Opinion Piece!
    Pharynx
    Polyp
    Polypectomy
    The Basics
    TSA

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